The Small Molecule Therapeutics SIG aims to have discussions, seminars and provide a platform for collaboration on interdisciplinary research that results in the identification of potent, safe, and pharmacokinetically desirable chemical entities as therapeutics against different disease areas. Discovery of small molecule therapeutics (molecular weight less than 750 Daltons) involves collaboration from scientists with expertise in target (protein) identification and validation, assay development, screening, lead molecule identification and optimization. Scientists with expertise in biology, medicinal chemistry, structural biology, cheminformatics, and computational chemistry (to name a few) are involved in this endeavor.
nicklaum@mail.nih.gov NCI Marc Nicklaus, Ph.D. https://irp.nih.gov/pi/marc-nicklaus hiroaki.mitsuya2@nih.gov Hiroaki Mitsuya, M.D., Ph.D. https://ccr.cancer.gov/staff-directory/hiroaki-mitsuya Scientific Interest Groups dasd@mail.nih.gov Debananda Das, Ph.D. https://list.nih.gov/cgi-bin/wa.exe?A0=SMALL-MOLECULE-THERAPEUTICS