Sample ELSI Applications and Summary Statements

Sample ELSI Applications and Summary Statements July 11, 2016

The grants listed below are examples of well-written applications and the associated summary statements that collectively represent a variety of grant mechanisms and research methodologies common to ethical, legal and social implications (ELSI) research.

Browse Samples Career Development Applications Research Applications Acknowledgement

We are grateful to the investigators and their institutions for allowing us to provide this important resource to the community. To maintain confidentiality, we have redacted some information from these documents (e.g., budgets, social security numbers, home addresses, introduction to revised application), where applicable. Most substantive components of the application (e.g. Project Abstract, Budget Justification, Specific Aims, Research Plan, and Human Subjects Protections) are included. We do not include other SF 424 (R&R) forms or requisite information found in the full grant application (e.g., budgets, biographical sketches, letters of recommendation or letters of support). NIH grant formats or rules may have changed since these applications were prepared; therefore, applicants should always follow the application format instructions included in the funding announcement.

Funding Opportunities

The NHGRI ELSI Research Program Funding Opportunities webpage contains a list of funding opportunities that NHGRI participates in related to ELSI research. The NHGRI Funding for Research Training webpage contains detailed information about research training and career development opportunities at the undergraduate, postbaccalaureate, graduate, postdoctoral and faculty levels. Funding opportunities vary in terms of eligibility requirements and area of research focus. Applicants are strongly encouraged to contact the appropriate NIH Scientific/Research contact listed in the Funding Opportunity well in advance of submitting the application.

k99-r00

Career Development Applications

K99/R00 Sample Applications and Summary Statements

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program provides independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers. Not all NIH Institutes and Centers participate in the K99/R00 mechanism. Applicants should carefully note which Institutes and Centers participate in funding announcements and view their respective areas of research interest and requirements prior to applying.

Title	Principle Investigator	Year of Submission	Application Resources
Use of Genetic Information by Life, Long-term Care, and Disability Insurers: Exploring International Lessons, the Domestic Legal Landscape, and Options for U.S Policy	Anya Prince	2015	Summary Statement Full Application
Ethical, Legal, and Social Implications of Translational Psychiatric Genomics Research	Gábriel Lazaro-Muñoz	2014	Summary Statement Full Application
Returning Exome and Whole Genome Results to Underserved Minority Populations	Joon-Ho Yu	2014	Summary Statement Full Application

k01

K01 Sample Applications and Summary Statements

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and “protected time” (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Not all NIH Institutes and Centers participate in the K01 mechanism. Applicants should carefully note which Institutes and Centers participate in funding announcements and view their respective areas of research interest and requirements prior to applying.

Title	Principle Investigator	Year of Submission	Application Resources
Impact of Psychiatric Genetic Data on Civil Litigation and its Relationship with Stigma	Maya Sabatello	2014	Summary Statement Full Application

r01

Research Applications

R01 Sample Applications and Summary Statements

The R01 mechanism is intended for well-integrated studies that build on preliminary data using either single or mixed methods.

Title	Principle Investigator(s)	Year of Submission	Application Resources
Addressing Ethical Challenges in Networked Biorepositories	Kyle Brothers Aaron Goldenberg	2015	Summary Statement Full Application
Clinical Integration of Whole Genome Sequencing: A Policy Analysis	David Kaufman Amy McGuire	2011	Summary Statement Full Application
Liability in the delivery of personalized medicine: driver, impediment, or both?	Gary E. Merchant	2011	Summary Statement Full Application
Anticipating Personal Genomic Medicine: Impact and Implications	Eric Juengst	2009	Summary Statement Full Application

r21

R21 Sample Applications and Summary Statements

The R21 grant mechanism is intended for projects that are primarily exploratory in nature or designed to generate pilot data in preparation for a larger study. The R21 mechanism provides a total of up to $275,000 in direct costs over two years.

Title	Principal Investigator(s)	Year of Submission
Using Ethics and User-Centered Design to Create Templates for EHR-Mediated Return of Genetic Test Results	Diane Korngiebel	2017	Summary Statement Full Application
Demographic Patterns of Eugenic Sterilization in California	Alexandra M. Stern	2015	Summary Statement Full Application
Returning Research Results of Pediatric Genomic Research to Participants	Ellen Clayton	2011	Summary Statement Full Application
Interactive Multimedia and Biorepository Informed Consent	Christian Simon David Klein Helen Schartz	2011	Summary Statement Full Application
Response to Testing Among Individual Consumers of DTC Personal Genomics Service	Cinnamon Bloss	2009	Summary Statement Full Application

r03

R03 Sample Applications and Summary Statements

The R03 grant mechanism is intended for small, self-contained research projects, such as those that involve single investigators. The R03 mechanism provides a total of up to $50,000 in direct costs a year for two years.

Title	Principle Investigator	Year of Submission	Application Resources
Intergenerational Monitoring in Clinical Trials of Germline Gene Editing: Ethical, Legal, and Social Issues	Bryan Cwik	2018	Summary Statement Full Application
Ethical, Legal, and Social Implications in Military Genomics	Maxwell Mehlman	2011	Summary Statement Full Application
Ecological Concepts of Human Identity in Microbiome and Metagenomic Research	Mark Sagoff	2010	Summary Statement Full Application

Biosketches

As of January 25, 2022, biosketches should be in the format described according to NIH Office of Extramural Research's Biosketch Format Pages, Instructions and Samples . That webpage also includes detailed instructions, FAQs, and examples of NIH biosketches.

A few sample biosketches written in the current format were generously contributed by the ELSI researchers listed below. Please note, these biosketches were current as of early 2023 but researchers may have had changes in position, institution, publications or grant funding since that time. These samples are provided as examples of approaches to writing an NIH biosketch and should not be copied.