AGI History and Guidance

“It would be fantastic if…”

The AGI began with the Audacious Goals Challenge , a prize competition that challenged participants to imagine the greatest achievement for vision research during the next 10-15 years. The challenge attracted more than 450 innovative proposals from around the world. The NEI consolidated the proposals into six themes, which were further explored by leading scientists at the Audacious Goals Development Meeting . In consultation with the National Advisory Eye Council, the NEI chose to pursue the goal of restoring vision through the regeneration of neurons and neural connections in the eye and visual system, specifically targeting the photoreceptors and retinal ganglion cells.

The NEI Audacious Goals Initiative: Bold research to restore vision j93k0e9GKqk

Did you know some of the common eye diseases involve damage to the retina and optic nerve? The National Eye Institute’s Audacious Goal Initiative aims to restore vision in these diseases. To learn more about how the eye works and what the AGI has in store, watch our new 3D animation.

AGI steering committee

The AGI Steering Committee plots the scientific trajectory of the AGI. Consisting of three to five leading researchers, the steering committee is responsible for identifying knowledge gaps and the scientific expertise needed to bridge them. The steering committee currently comprises five members:

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Len Levin
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Mike Dyer
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Clive Svendsen
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Russ VanGelder
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Rachel Wong

The National Advisory Eye Council (NAEC) provides administrative guidance to the NEI. The NAEC consists of 12 recognized leaders in the fields of ophthalmology, optometry, and basic sciences. The NAEC advises the NEI director on AGI funding plans and provides a second level of review on proposals to AGI funding opportunities.

Learn more about the National Advisory Eye Council (NAEC) Office of Regenerative Medicine at NEI

The NEI Office of Regenerative Medicine provides logistical support for all AGI-related activities.

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AGI Working Group

The AGI Working Group comprises of staff within the Division of Extramural Science Programs and the Division of Extramural Activities , who help draft funding announcements, monitor the progress of research programs, and make recommendations to the AGI Steering Committee, the NAEC, and the NEI Director.

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Donald Everett
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Cheri Wiggs
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Sangeeta Bhargava PhD
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