Health Equity: Inclusion and retention of underrepresented populations in clinical research

AD-Related Dementias Focus

Leverage ongoing initiatives on the science of inclusion to facilitate community engagement, understanding, recruitment, and long-term retention of populations experiencing AD/ADRD health disparities.

2023 NOT-NS-21-047: Administrative Supplements to Promote Diversity for NINDS Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) Awardees RFA-AG-23-020: Building Infrastructure for Precision Medicine Research on Minority Health and Disparities in Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD) (UH2/UH3 Clinical Trial Not Allowed) 12.K Achieved Develop novel and identify existing community engagement and outreach methods to facilitate engagement, understanding and partnership with health disparities populations. DN 2016 ADRD Summit: Health Disparities (HD) Focus Area 4: Community Partnerships, Recruitment, and Retention, Recommendation 7 (PDF, 901K)) Workshop: Health Disparities and Inequities in Neurological Disorders Blog: Customize your dementia clinical trial recruitment materials with OutreachPro! Blog: Join us March 22 for a webinar on building more inclusive Alzheimer’s studies Workshop: Examining Diversity, Recruitment, and Retention in Alzheimer's Disease(AD) and AD-Related Dementias Research (147 KB, PDF) Recruitment and Citizen Engagement

ADORE: Alzheimer’s and Dementia Outreach, Recruitment and Engagement Resources National Strategy for Recruitment and Participation in Alzheimer's and Related Dementias Clinical Research NIA’s Clinical Research Operations & Management System (CROMS) Select projects funded in FY21 Select projects Funded in FY22 Addition of Formative Research Takeaways for Development of OutreachPro Messaging

  • At least one new project to develop new community-based strategies to recruit, retain, and engage study participants from diverse populations.
  • Develop, disseminate, and implement a national strategy for AD/ADRD clinical research to increase engagement and retention of diverse patients and caregivers.
  • Track subject recruitment in clinical trials by gender, race/ethnicity, socioeconomic status, geographic region, and other key features.

Summary of Key Accomplishments

The NIA Health Disparities Research Framework showcases priorities and investments in this important aging research area. The Framework outlines four key levels of analysis related to disparities research–environmental, sociocultural, behavioral, and biological—with priority focus areas in each level. This framework complements the NIA National Strategy for Recruitment and Participation in Alzheimer's and Related Dementias Clinical Research.

The key accomplishments summary is current as of July 2022.