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Initiate 3-4 clinical research studies using common standard outcome measures.
2020 10.C Achieved Initiate 3-4 clinical research studies using common standard outcome measures... DN 2012 AD Summit: 5E Trial Design Alzheimer’s Prevention Initiative (API) Anti-Amyloid Treatment In Asymptomatic Alzheimer’s Disease Study (A4 study) Dominantly Inherited Alzheimer's Network Trials Unit - Adaptive Prevention Trial (DIAN-TU) Collaboration for Alzheimer’s Prevention (CAP): Prevention Trials 2015
- Data comparisons conducted from clinical studies using common standard outcome measures.
Summary of Key Accomplishments
Three secondary prevention trials supported by NIA (A4, API, DIAN-TU) are using several common outcome measures such as CDR (clinical dementia rating), WMS (Wechsler Memory Scale), amyloid and tau PET, CSF amyloid, and others. In addition, the NIA supported natural history studies (ADNI, DIAN, ABC-DS, HABS-HD and LEADS) are using several common outcome measures enabling data comparisons across multi-ethnic populations and different types of early and late onset AD.
The key accomplishments summary is current as of March 2022.