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Establish a working group to identify standard outcome measures necessary for data comparisons across secondary prevention trials.
2015 10.B Achieved Establish a working group to identify standard outcome measures necessary for data comparisons across secondary prevention trials... DN 2012 AD Summit: 5E Trial Design Alzheimer’s Prevention Initiative (API) Anti-Amyloid Treatment In Asymptomatic Alzheimer’s Disease Study (A4 study) Dominantly Inherited Alzheimer's Network Trials Unit - Adaptive Prevention Trial (DIAN-TU) Collaboration for Alzheimer’s Prevention (CAP): Prevention Trials 2014
- Identification of at least two standard outcome measures for data comparison in clinical research.
Summary of Key Accomplishments
NIA is one of founding members in the Collaboration for Alzheimer’s Prevention (CAP) working group that brings together representatives from academia, industry, the non-profit and industry sector, NIA and FDA.
The CAP working group established recommendations for harmonizing prevention trials procedures, cognitive and clinical outcomes, and clinical trials data and biosamples sharing. Identified common outcome measures include the CDR (clinical dementia rating), WMS (Wechsler Memory Scale), amyloid and tau PET, CSF amyloid, and more.
The key accomplishments summary is current as of March 2022.