This study asked Mexicans and Mexican Americans at risk for autosomal dominant Alzheimer’s disease about their interest in participating in four hypothetical clinical trial scenarios, each with a different level of perceived invasiveness. The authors found that people living in rural Mexico were more willing to participate and that altruism toward future generations is a major motivation. The main reasons for refusal to participate were not wanting to undergo genetic testing and concern about adverse effects.
Zuno-Reyes A, et al. Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer's disease. Alzheimers Res Ther. 2022;14(1):173. doi: 10.1186/s13195-022-01114-4.
f3a640a4849ba155afb591a4763ee2c8 Recruit & Retain Participants 2023-03-03T00:00:00Z Barriers & Facilitators Hispanic or Latino Rural or Urban Underrepresented Research Articles