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Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors

Good-quality studies comparing traditional risk assessment with traditional risk assessment plus the ABI, hsCRP level, or CAC scores to measure the effect of adding nontraditional risk factors on clinical decision thresholds and patient outcomes (CVD events; mortality).
Studies are needed in more diverse populations (women, racial/ethnic minorities, persons of lower socioeconomic status) in whom assessment of nontraditional risk factors may help address the shortcomings of traditional risk models.
Well-designed prospective studies reflective of real-world practice to identify the downstream effects of CAC score on additional testing and procedures.

The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of using the nontraditional risk factors studied to screen asymptomatic men and women with no history of CVD to prevent CVD events.

Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors Read full statement 1