Pragmatic and Group-Randomized Trials in Public Health and Medicine

Questions about this course?

The Pragmatic and Group-Randomized Trials in Public Health and Medicine online course is presented by Dr. David M. Murray, the NIH Associate Director for Prevention and Director of ODP. This course, updated in September 2024, is meant to help researchers design trials involving groups or clusters.

Course Videos

Part 1: Randomized Designs for Clinical Trials

Part 2: Analytic Methods

Part 3: Sample Size and Power

Part 4: Alternative Designs

Related Materials

Considering a trial involving groups or clusters?

Check out NIH's Research Methods Resources website .

For more information about GRTs, watch these additional videos from our Methods: Mind the Gap webinar series and ODP Director Dr. David M. Murray.

Research Methods Resources for Clinical Trials Involving Groups or Clusters
Design and Analysis of Individually Randomized Group-Treatment Trials in Public Health
Stepped Wedge Cluster Randomized Designs for Disease Prevention Research
Pragmatic Trials Involving Group Randomization or Delivery of Interventions to Groups: GRTs, IRGTs, and SW-GRTs