NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive...

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TitleNTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive...
SubjectNTP conducted a multigenerational study (modified one-generation; MOG) in rodents to assess the potential for continual exposure to 2-ethylhexyl p-methoxycinnamate (EHMC) via the diet to affect reproduction and development and induce subchronic toxicity. Full title: NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive Performance, and Subchronic Assessments in F1 Offspring
Purpose (e.g., abstract)This peer review done via panel conducted in Q2 2021. It will assess of the draft NTP developmental and reproductive toxicity technical report (DART-06). Information for the review will be posted once dates are finalized.
Information Product Contact
ISI or HISAisi
ICNIEHS
IC Division, Office, or ProgramDivision of the National Toxicology Program
NIH ContactSheena Scruggs
984-287-3355
sheena.scruggs@nih.gov
Reviewer Names and Expertise
Review DescriptionExternal scientists will peer review the draft report via letter.
Date of Review2021-05-01
Number of Reviewers2-3
Upcoming Panels, Eventshttps://ntp.niehs.nih.gov/events/past/index.html?utm_source=direct&utm_medium=prod&utm_campaign=ntpgolinks&utm_term=meeting
Technical/Draft Reports, Public Comments and Presentationshttps://ntp.niehs.nih.gov/events/panels/index.cfm
Past Roster, Notices, Meeting Updateshttps://ntp.niehs.nih.gov/events/past/index.html?utm_source=direct&utm_medium=prod&utm_campaign=ntpgolinks&utm_term=meeting
Reviewer Expertisepathology, general tox, reproductive/developmental biology
How SelectedNTP selected from identified experts
Opportunity for Public Comment?yes
Agenda Date2020-12-16