Office of Intramural Research (OIR)

Our mission

The National Institutes of Health is the steward of medical and behavioral research for the Nation. Its mission is science in pursuit of fundamental knowledge about the nature and behavior of living systems, and the application of that knowledge to extend healthy life and reduce the burdens of illness and disability. Within this framework, the mission of the Office of Intramural Research (OIR) is to enable the NIH Intramural Research Program (IRP) to:

The human gut teems with bacteria and other microbes. They contribute to our health but also influence our susceptibility to certain diseases, including Alzheimer’s disease.
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Leadership

Leadership of the NIH Office of Intramural Research (OIR) comprises the NIH Deputy Director for Intramural Research (DDIR) and a cadre of senior representatives for all intramural activities.

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Offices

OIR is comprised of several offices and enterprise programs focused on various aspects of intramural research, training, and technology transfer.

Intramural Research Program (IRP)

The Intramural Research Program (IRP) is the internal research program of the NIH, known for its synergistic approach to biomedical science. 

Check Out the IRP

Scientific Interest Groups (SIGs)

NIH Intramural Scientific Interest Groups (SIGs) are assemblies of scientists with common research interests.

Learn More About SIGs

Lectures & Events

OIR organizes the NIH Director’s Wednesday Afternoon Lecture Series (WALS),  The Demystifying Medicine Series and The NIH Research Festival

Learn About our Lectures & Events

Sourcebook

The NIH intramural ‘sourcebook’ is a compendium of policies and resources for the NIH scientific research community.

Visit the Sourcebook

CRISPI

CRISPI (Clinical Research Informatics Supporting Principal Investigators) is the NIH's vision for a modern clinical research informatics ecosystem.

Learn About CRISPI

NIDB

The NIH Intramural Database (NIDB) collects and disseminates information about research being performed in the Intramural Programs

Visit the NIDB