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ODP is coordinating the ADVANCE (ADvancing preVention intervention reseArch in populatioNs that experienCe health disparitiEs) initiative across NIH. ADVANCE is a research effort that grew out of ODP’s portfolio analysis of NIH research. In an examination of NIH-funded grants and cooperative agreements between fiscal years 2012 and 2017, ODP found that only 8.5% of all projects focused on preventing the leading risk factors or causes of death and disability (e.g., poor nutrition, low physical activity, smoking), falling well below their burden on the nation’s health.
An additional analysis of the NIH research portfolio showed that between fiscal years 2016 and 2019, only 3.6% of NIH-funded prevention projects included a randomized intervention to address a leading risk factor for death or disability in populations that experience health disparities. Looking at the NIH research portfolio as a whole, only 0.75% of all NIH-funded research in 2019 included a randomized intervention to prevent the leading risk factors or causes of death and disability in populations that experience health disparities.
ADVANCE brings together NIH Institutes, Centers, and Offices to address this need for additional research. It will concentrate on developing new prevention interventions and strategies to deliver existing evidence-based interventions and preventive services in populations that experience health disparities.
ODP looks forward to sharing more as the effort evolves.
Funding opportunities
- Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities [NOT-OD-22-154]. Due dates vary by awarding NIH Institute, Center, or Office. Expires September 8, 2025.
- Notice of Special Interest (NOSI): Interventions to promote mental well-being in populations that experience health disparities through social, cultural, and environmental connectedness [NOT-OD-23-194]. Due dates vary by awarding NIH Institute, Center, or Office. Expires September 8, 2026.
- Interventions To Expand Cancer Screening and Preventive Services To ADVANCE Health in Populations that Experience Health Disparities (R01, Clinical Trial Required) [PAR-25-098]. Next due date: February 5, 2025. Expires January 8, 2027.
- Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) [PAR-26-001]. Next due date: February 5, 2025. Expires May 8, 2027.
Announcements
- Quit & Thrive Challenge: Community-Derived Solutions to Reduce Menthol Cigarette Smoking. ODP sponsored the Quit & Thrive Challenge: Community-Derived Solutions to Reduce Menthol Cigarette Smoking to enhance the evidence base of interventions for populations with high levels of menthol cigarette smoking. This Challenge encouraged submissions from local and state organizations and agencies to highlight successful community-led solutions that address menthol cigarette smoking. In March 2026, ODP awarded prizes to 12 organizations with the most successful or innovative community-led strategies. Information about the winning submissions can be found on the NIH Challenge page.
- Art Challenge: How Prevention Can Create Better Health for Everyone. In May 2024, ODP announced the winning artwork for its 2023 youth art challenge, How Prevention Can Create Better Health for Everyone. Ten teens and young adults were awarded for their pieces showing what people and communities can do to help advance health equity by preventing illness and injury.