- Long-term data on the effectiveness of screening for and treatment of lipid disorders in children and adolescents to prevent premature cardiovascular events or death in adulthood.
- Measurement of the diagnostic yield of lipid screening tests through confirmatory lipid and genetic testing to identify children and adolescents with FH and multifactorial dyslipidemia.
- Comparative effectiveness data assessing the optimal age at which to start lipid-lowering interventions for maximal benefit in children and adolescents diagnosed with FH or multifactorial dyslipidemia, including benefits and harms of starting pharmacologic treatment as a child (eg, ages 8 to 10 years) vs as a young adult (early 20s).
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for lipid disorders in children and adolescents 20 years or younger.
Lipid Disorders in Children and Adolescents: Screening Read full statement