How to navigate a NOFO

Use the Table of Contents

The best place to start is the NOFO’s Table of Contents, which typically includes hyperlinks to the key dates and the full funding opportunity description. Additionally, you can quickly find award and eligibility information; application, submission, review, and award administration details; and agency contacts.

What is this NOFO about?

There are two parts of a NOFO that explain the proposed research it will support: the Funding Opportunity Purpose and the Funding Opportunity Description. The purpose, located in “Part 1. Overview Information,” is a brief summary of what NIH hopes to accomplish through the NOFO, while “Part 2, Section 1. Funding Opportunity Description” goes into much more detail about the background and scope of the opportunity.

So, read the purpose to see if a NOFO might be of interest to you, and if you like what you see there, head to “Part 2, Section I” to read the description.

Who can apply?

Once you’ve determined that you’re interested in applying, you’ll want to ensure you and your institution are eligible for funding through the NOFO. “Part 2, Section III. Eligibility Information” contains the detailed criteria on who may apply.

It’s also a good idea to check the “Components of Participating Organizations” list in Part 1 to ensure the NIH Institute or Center you’re targeting is participating in the NOFO. And don’t forget to review “Part 2, Section II. Award Information” to see what types of applications are allowed and whether clinical trials applications will be funded.

How do I apply?

Now it’s time to apply! You’ll need to start generating the necessary documents for the application. Read through the instructions on how to fill out and submit your application package in “Part 2, Section IV. Application and Submission Information.” Pay close attention to the details included in “Subsection 2, Content and Form of Application Submission” — this guidance supersedes the standard NIH application instructions .

In addition, check the Funding Opportunity Description to see if the NOFO has responsiveness criteria that your application must meet in order to be reviewed. And finally, complete the required registrations listed in the Eligibility Information section before submitting your application.

Speaking of submitting your application, don’t forget to take note of when applications are due! You’ll find this information in the “Key Dates” portion of “Part 1. Overview Information.” Remember to also familiarize yourself with your institution’s internal deadlines so you know how far in advance you’ll need to have your final materials ready.

Learn more!

NOFOs can be complicated, especially if you’re new to the NIH grant application process. But familiarizing yourself with how they are structured will make applying easier. I underscore that it’s always critical to read the entire NOFO to ensure you are meeting all the requirements.

In the meantime, if you have questions about the NOFO you’re reading, we always encourage potential applicants to talk to the program officers listed as scientific/research contacts in “Part 2, Section VII, Agency Contacts.” You can also connect with NIA’s training and career development team or head to the NIH website to learn more about funding opportunities in general. Or feel free to leave a question or comment below!

Applications Funding Opportunities Success Rates 2024-03-20T00:00:00Z