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Create a National IRB.
2015 RFA-TR-15-002: CTSA Network - Trial Innovation Centers (TICs) (U24) RFA-AG-17-005: Alzheimer's Clinical Trials Consortium (ACTC) (U24) PAR-18-513: Alzheimer's Clinical Trials Consortium (ACTC) Clinical Trials (R01) 4.I Achieved DN 2012 AD Summit: 3H 2015 AD Summit: 3H News: New NIH consortium award to enhance clinical trials for Alzheimer’s disease, related dementias Blog: A new era of clinical trials in Alzheimer’s disease and related dementias Translational Tools, Infrastructure, and Capabilities NIH Single IRB Policy for Multi-site Research Alzheimer’s Clinical Trials Consortium (ACTC) NCATS: CTSA Trial Innovation Network 2014
- Initiation of at least one multi-center clinical trial that utilizes a national IRB.
Summary of Key Accomplishments
NIA provides co-funding for one of the Trial Innovation Centers established by the National Center for Advancing Translational Sciences focused on aging and dementia. A key feature of each center within the Trial Innovation Centers network is to provide centralized IRB services. Centralized IRB is also an essential element of NIA’s Alzheimer’s Clinical Trials Consortium. The Consortium conducts multi-site clinical trials for the treatment and prevention of AD/ADRD, and has launched two clinical trials (A3 and A45) that utilize the centralized IRB.
The key accomplishments summary is current as of March 2022.