NTP Technical Report on the Toxicology and Carcinogenesis Studies of Alpha-Pinene (CASRN 80-56-8) Administered by Inhalation to Sprague Dawley (Hsd: Sprague Dawley® SD®) Rats, B6C3F1/N Mice, and CD1 Mice

Document, Report, or Other Product Information
TitleNTP Technical Report on the Toxicology and Carcinogenesis Studies of Alpha-Pinene (CASRN 80-56-8) Administered by Inhalation to Sprague Dawley (Hsd: Sprague Dawley® SD®) Rats, B6C3F1/N Mice, and CD1 Mice
SubjectThe National Toxicology Program conducted 2-year toxicology and carcinogenesis studies of alpha-pinene in rodents to evaluate long-term toxicity and potential to cause cancer.
Purpose (e.g., abstract)To conduct external peer review of the 2-year toxicology and carcinogenesis studies.
Information Product Contact
ISI or HISAisi
ICNIEHS
IC Division, Office, or ProgramDivision of Translational Toxicology
NIH ContactMary Wolfe
984-287-3209
wolfe@niehs.nih.gov
Reviewer Names and Expertise
Review DescriptionExternal peer review of the technical and scientific elements of the study and whether they support the conclusions.
Date of Review2025-05-28
Number of Reviewers7
Past Roster, Notices, Meeting Updateshttps://ntp.niehs.nih.gov/events/past?type=Expert%20Panels
Reviewer Expertisecarcinogenicity, general pathology, molecular pathology, reproductive pathology and toxicology, inhalation toxicology, general toxicology, monoterpenes, genetic toxicology
How SelectedNTP selected from scientific experts, taking into account expertise, geographical location, independence, and free of COI.
Opportunity for Public Comment?no
Did any reviewers require any exception to the applicable independence or COI standards of the Bulletin, including determination by the Sec./Dep. Sec. pursuant to Section (3)(c)?no
Were any waivers, deferrals, exemptions, or alterative peer review processes used?no
Any Public Meetings?no
Were Reviewers Solicitedno
Agenda Date2024-12-16