NTP Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CAS No. 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats

Document, Report, or Other Product Information
TitleNTP Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CAS No. 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats
SubjectNTP assessed the potential of continual exposure to 2-hydroxy-4-methoxybenzophenone (2H4MBP) via the diet to induce developmental toxicity, affect reproductive performance (e.g., pregnancy rate, litter size), and alter endocrine-sensitive endpoints, and included histopathological examination of the adult F1 male and female reproductive tracts.
Purpose (e.g., abstract)This peer review done via panel will be conducted in Q2 2021. It will assess of the draft NTP developmental and reproductive toxicity technical report (DART-05). Information for the review will be posted once dates are finalized.
Information Product Contact
ISI or HISAisi
ICNIEHS
IC Division, Office, or ProgramDivision of the National Toxicology Program
NIH ContactSheena Scruggs
984-287-3355
sheena.scruggs@nih.gov
Reviewer Names and Expertise
Review DescriptionExternal scientists will peer review the draft report via letter.
Date of Review2021-05-01
Number of Reviewers2-3
Upcoming Panels, Eventshttps://infoquality.osp.od.nih.gov/%20https://ntp.niehs.nih.gov/events/past/index.html?utm_source=direct&utm_medium=prod&utm_campaign=ntpgolinks&utm_term=meeting
Technical/Draft Reports, Public Comments and Presentationshttps://ntp.niehs.nih.gov/events/panels/index.cfm
Past Roster, Notices, Meeting Updateshttps://infoquality.osp.od.nih.gov/%20https://ntp.niehs.nih.gov/events/past/index.html?utm_source=direct&utm_medium=prod&utm_campaign=ntpgolinks&utm_term=meeting
Reviewer Expertisepathology, general tox, reproductive/developmental biology
How SelectedNTP selected from identified experts
Opportunity for Public Comment?yes
Agenda Date2020-12-16