Maximizing Investigators' Research Award (MIRA) (R35)

MIRA provides support for research in an investigator's laboratory that falls within the mission of NIGMS . The goal of MIRA is to increase the efficiency of NIGMS funding by providing investigators with greater stability and flexibility, thereby enhancing scientific productivity and the chances for important breakthroughs. The program will also help distribute funding more widely among the nation's highly talented and promising investigators. MIRA grants will generally be for 5 years, for both established investigators/ new investigators and early stage investigators . With the publication of PAR-26-121 , the program has now expanded to include established investigators who currently hold an NIGMS R01-equivalent grant or who wish to renew a MIRA, as well as new investigators who are not serving as a subproject leader on any multicomponent awards and propose research in the NIGMS mission. Early stage investigators should apply through PAR-23-145 .

MIRA Welcome Letter

MIRA for Established and New Investigators (EIs and NIs)
New NOFO Published: PAR-26-121

See below for MIRA for Early-Stage Investigators (ESIs).

PAR-26-121 – Applications accepted in 2026-2028

FAQs About MIRA PAR-22-180

MIRA Eligibility for Administrative Supplements

mira-eligibility-decision-tree-01-2023.pdf (80.97 KB)

EINI_MIRA_Slides.pdf (498.9 KB)

For more information on MIRA for established investigators contact Ashley Barnes, Ph.D., and Baishali Maskeri, Ph. D., at NIGMS_EINIMIRA@nigms.nih.gov