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Special Emphasis Panel for Drug Discovery and Molecular Pharmacology – ACT (80)
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Scientific Review Officer
Applications focused on early stages of discovery and development of novel anti-cancer agents including small molecule inhibitors, natural products, peptides, proteins, peptidomimetics, and immunomodulators.
Review Dates
Topics
- Initial discovery methods including High-throughput (HTS) assay development, primary screen implementation.
- Molecular characterization of new anti-cancer agents, including mechanism of action, structural characterization of enzyme-inhibitor complexes, and confirmation of target engagement.
- Medicinal chemistry focused on lead selection for cancer therapy.
- Development of mathematical and computational methods for the investigation of therapeutic strategies.